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The peptide works through signaling mechanisms rather than concentration-dependent effects, meaning you do not need more simply because you have more tissue

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doi: 10.3389/fimmu.2026.1769281 Received 16 December 2025 Revised 08 April 2026 Accepted 13 April 2026 Published 29 April 2026 Volume 17 - 2026 Edited by Douglas Sborov, The University of Utah, United States Reviewed by Noémie Leblay, University of Calgary, Canada Xuan Jiang, Shanghai Jiao Tong University, China Updates Copyright © 2026 Horenstein, Frerichs, Faini, van de Donk and Malavasi